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          Recombinant Human 4-1BB/TNFRSF9(His Tag)
           
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          產(chǎn)品信息
          


          
	
		
          
			
			
          產(chǎn)品名稱
          
			          		
			
			
          產(chǎn)品編號
          
			          		
			
			
          規(guī)格
          
			          		
		
          
		
          
			
			
          Recombinant Human 4-1BB/TNFRSF9 (His Tag)
          
			          		
			
			
          93544ES25
          
			          		
			
			
          25 μg
          
			          		
		
          
		
          
			
			
          93544ES60
          
			          		
			
			
          100 μg
          
			          		
		
          
		
          
			
			
          93544ES76
          
			          		
			
			
          500 μg
          
			          		
		
          
		
          
			
			
          93544ES80
          
			          		
			
			
          1 mg
          
			          		
		
          
	          

          


           
          


          產(chǎn)品描述
          


          4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
          


           
          


          產(chǎn)品性質(zhì)
          


          
	
		
          
			
			
          別名（Synonyms）
          
			          		
			
			
          CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
          
			          		
		
          
		
          
			
			
          Uniprot No.
          
			          		
			
			
          Q07011
          
			          		
		
          
		
          
			
			
          表達區(qū)間及表達系統(tǒng)（Source）
          
			          		
			
			
          HEK293 Cells-derived Human 4-1BB/TNFRSF9 Protein, Leu24-Gln186 with His tag at the C-terminal
          
			          		
		
          
		
          
			
			
          分子量(Molecular Weight)
          
			          		
			
			
          Approximately 18.1 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
          
			          		
		
          
		
          
			
			
          外觀(Physical Appearance）
          
			          		
			
			
          Sterile Filtered White lyophilized (freeze-dried) powder.
          
			          		
		
          
		
          
			
			
          純度（Purity）
          
			          		
			
			
          > 95% as determined by SDS-PAGE and HPLC
          
			          		
		
          
		
          
			
			
          活性（Activity）
          
			          		
			
			
          ELISA Data: Immobilized Human 4-1BB, His Tag at 1μg/mL (100 μL/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.7 ng/mL determined by ELISA.
          
			          		
		
          
		
          
			
			
          內(nèi)毒素（Endotoxin）
          
			          		
			
			
          < 1.0 EU per 1μg of the protein by the LAL method.
          
			          		
		
          
		
          
			
			
          制劑（Formulation）
          
			          		
			
			
          Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
          
			          		
		
          
		
          
			
			
          復溶（Reconstitution）
          
			          		
			
			
          Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
          
			          		
		
          
	          

          


           
          


          運輸與保存方法
          


          冰袋運輸。-20℃至-80℃保存，一年有效期。
          


          復溶后，-20 至 -80°C，在未開封狀態(tài)下保存 3-6 個月。復溶后，2-8°C 保存 2-7 天。
          


          建議第一次使用時分裝凍存，避免反復凍融。
          


           
          


          注意事項
          


            
	
          1. 避免反復凍融。
            2. 
	
          2. 為了您的安全和健康，請穿實驗服并戴一次性手套操作。
            3. 
	
          3. 本產(chǎn)品僅作科研用途！
            4. 

          

          


           
          


          產(chǎn)品數(shù)據(jù)
          


          Tris-Bis PAGE 
          



          

          


          SEC-HPLC 
          



          

          


          ELISA Data
          



          

          


           
          


          HB240312
          


           
          

             
           
           
           
           
           
           
           
          400-6111-883